Pub. Date : 2021
PMID : 33623415
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GSTA1 genotypes, body surface area (BSA) and aspartate aminotransferase (AST) were found to be significant covariates of Bu clearance, and BSA had significant impact of the volume of distribution. | Busulfan | glutathione S-transferase alpha 1 | Homo sapiens |
| 2 | Conclusion: We recommend a GSTA1-BSA and BSA-based dosing (Q6 h) based on a PPK model for personalizing busulfan therapy in pediatric population. | Busulfan | glutathione S-transferase alpha 1 | Homo sapiens |