Pub. Date : 2021 Mar 12
PMID : 33614822
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we examined whether vinblastine (a multiple drug resistance 1 [MDR1] substrate) could remove residual undifferentiated hiPSCs in hiPSC-IECs and attempted to generate hiPSC-IECs applicable to transplantation medicine. | Vinblastine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | In this study, we examined whether vinblastine (a multiple drug resistance 1 [MDR1] substrate) could remove residual undifferentiated hiPSCs in hiPSC-IECs and attempted to generate hiPSC-IECs applicable to transplantation medicine. | Vinblastine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | We hypothesized that MDR1-negative cells (such as undifferentiated hiPSCs) die upon vinblastine treatment because they are unable to excrete vinblastine. | Vinblastine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | As expected, the cell viability of MDR1-knockout hiPSC-IECs was significantly decreased by vinblastine treatment. | Vinblastine | ATP binding cassette subfamily B member 1 | Homo sapiens |