Title : TNFα enhances trovafloxacin-induced in vitro hepatotoxicity by inhibiting protective autophagy.

Pub. Date : 2021 May 15

PMID : 33609687






1 Functional Relationships(s)
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1 Phosphorylation of p70S6K was inhibited by siRNA knockdown and rapamycin to restore TNFalpha-inhibited autophagy, which prevented the synergistic effect on TVX-induced cytotoxicity. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens