Title : Impact of diabetes on promoting the growth of breast cancer.

Pub. Date : 2021 May

PMID : 33609419






2 Functional Relationships(s)
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1 RESULTS: Treatment with metformin/rosiglitazone in MMTV-ErbB2/Leprdb/db mouse model reduced serum insulin levels, prolonged overall survival, decreased cumulative tumor incidence, and inhibited tumor progression. Metformin erb-b2 receptor tyrosine kinase 2 Homo sapiens
2 The tumor cells from MMTV-ErbB2/Leprdb/db transgenic mice treated with metformin had reprogrammed metabolism by reducing levels of both oxygen consumption and lactate production. Metformin erb-b2 receptor tyrosine kinase 2 Homo sapiens