Title : Angiotensin II-induced histone deacetylase 5 phosphorylation, nuclear export, and Egr-1 expression are mediated by Akt pathway in A10 vascular smooth muscle cells.

Pub. Date : 2021 Apr 1

PMID : 33606583






1 Functional Relationships(s)
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1 Further, pharmacological inhibition of HDAC5 by MC1568 or TMP-195, or knockdown of HDAC5 and the blockade of the nuclear export of HDAC5 by leptomycin B or KPT-330 significantly reduced Ang II-induced Egr-1 expression. MC1568 histone deacetylase 5 Homo sapiens