Title : Tetracyclines, a promise for neuropsychiatric disorders: from adjunctive therapy to the discovery of new targets for rational drug design in psychiatry.

Pub. Date : 2021 Apr 1

PMID : 33595954






1 Functional Relationships(s)
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1 In a reverse translational approach, tetracyclines inhibit microglial reactivity and toxic inflammation by mechanisms related to the inhibition of nuclear factor kappa B signaling, cyclooxygenase 2, and matrix metalloproteinases. Tetracyclines prostaglandin-endoperoxide synthase 2 Homo sapiens