Pub. Date : 2021 Oct 5
PMID : 33588721
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The rs4680 SNP (COMT and D2 receptor genes) is associated with antipsychotic-induced dopamine hypersensitivity and pharmacotherapy resistance. | Dopamine | catechol-O-methyltransferase | Homo sapiens |
| 2 | The function of risk genes is described: COMT and MAO A/B genes, with a reduced activity in the corresponding enzymes, are associated with a decrease in dopamine degradation and hence dopamine hyperactivity occurred via D2 receptors. | Dopamine | catechol-O-methyltransferase | Homo sapiens |
| 3 | The function of risk genes is described: COMT and MAO A/B genes, with a reduced activity in the corresponding enzymes, are associated with a decrease in dopamine degradation and hence dopamine hyperactivity occurred via D2 receptors. | Dopamine | catechol-O-methyltransferase | Homo sapiens |