Pub. Date : 2021 Apr 1
PMID : 33587348
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | LncRNA highly upregulated in liver cancer regulates imatinib resistance in chronic myeloid leukemia via the miR-150-5p/MCL1 axis. | Imatinib Mesylate | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
2 | MCL1 bound to miR-150-5p and reversed the effect of HULC on imatinib resistance. | Imatinib Mesylate | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |
3 | These findings indicated that HULC enhanced imatinib resistance in CML by modulating the miR-150-5p/MCL1 axis, providing a promising biomarker for CML. | Imatinib Mesylate | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |