Title : LncRNA highly upregulated in liver cancer regulates imatinib resistance in chronic myeloid leukemia via the miR-150-5p/MCL1 axis.

Pub. Date : 2021 Apr 1

PMID : 33587348






3 Functional Relationships(s)
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1 LncRNA highly upregulated in liver cancer regulates imatinib resistance in chronic myeloid leukemia via the miR-150-5p/MCL1 axis. Imatinib Mesylate MCL1 apoptosis regulator, BCL2 family member Homo sapiens
2 MCL1 bound to miR-150-5p and reversed the effect of HULC on imatinib resistance. Imatinib Mesylate MCL1 apoptosis regulator, BCL2 family member Homo sapiens
3 These findings indicated that HULC enhanced imatinib resistance in CML by modulating the miR-150-5p/MCL1 axis, providing a promising biomarker for CML. Imatinib Mesylate MCL1 apoptosis regulator, BCL2 family member Homo sapiens