Title : miR-18a promotes glioblastoma development by down-regulating ALOXE3-mediated ferroptotic and anti-migration activities.

Pub. Date : 2021 Feb 12

PMID : 33579899






1 Functional Relationships(s)
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1 Furthermore, ALOXE3 silencing promoted 12-hydroxyeicosatetraenoic acids (12-HETE) secretion from GBM cells, in turn, 12-HETE enhanced migration of GBM cells by activating Gs-protein-coupled receptor (GsPCR)-PI3K-Akt pathway in an autocrine manner. 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid arachidonate lipoxygenase 3 Mus musculus