| Protein Name | arachidonate lipoxygenase 3 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 23801 |
| Gene Symbol | Aloxe3 |
| UniProt | Q9WV07 (LOXE3_MOUSE), Q14B96 (Q14B96_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
27
Total Number of Articles : 9 |
Description |
arachidonate lipoxygenase 3 |
| Gene Summary |
Enables hydroperoxy icosatetraenoate isomerase activity. Involved in several processes, including establishment of skin barrier; long-chain fatty acid metabolic process; and peroxisome proliferator activated receptor signaling pathway. Predicted to be located in cytoplasm and membrane. Is expressed in epidermis and skin. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1 and autosomal recessive congenital ichthyosis 3. Orthologous to human ALOXE3 (arachidonate epidermal lipoxygenase 3). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |