Title : Dantrolene Potentiates the Antineoplastic Effect of Sorafenib in Hepatocellular Carcinoma via Targeting Ca+2/PI3K Signaling Pathway.

Pub. Date : 2021

PMID : 33573585






1 Functional Relationships(s)
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1 RESULTS: Dantrolene exhibited synergistic effect when used in combination with sorafenib compared to either drug alone (p <0.05) through decreasing p53, VEGF, MMP-9, Cyclin D1, and Ki-67. Sorafenib matrix metallopeptidase 9 Rattus norvegicus