Protein Name matrix metallopeptidase 9
Organism Rattus norvegicus
Gene ID 81687
Gene Symbol

Mmp9

UniProt P50282 (MMP9_RAT)
Relationships Total Number of functionally related compound(s) : 821
Total Number of Articles : 1195
Description

matrix metallopeptidase 9

Gene Summary

Enables fibronectin binding activity and metallopeptidase activity. Involved in several processes, including cellular response to cell-matrix adhesion; cellular response to cytokine stimulus; and cellular response to iron(III) ion. Located in extracellular space. Part of protein-containing complex. Used to study artery disease (multiple); brain ischemia (multiple); congestive heart failure; glomerulosclerosis; and lung disease (multiple). Biomarker of several diseases, including artery disease (multiple); brain disease (multiple); chronic obstructive pulmonary disease (multiple); glucose metabolism disease (multiple); and kidney disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; anodontia; artery disease (multiple); autoimmune disease (multiple); and chronic obstructive pulmonary disease (multiple). Orthologous to human MMP9 (matrix metallopeptidase 9). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • matrix metalloproteinase-9
  • 92 kDa gelatinase
  • 92-kDa type IV collagenase
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Properties