Pub. Date : 2021
PMID : 33568030
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Furthermore, the inhibitions of clotrimazole towards hCE2-mediated hydrolysis of FD, NCEN and CPT-11 were all in competitive mode with the Ki values of 0.483 muM, 8.63 muM and 29.0 muM, respectively. | Irinotecan | carboxylesterase 2 | Homo sapiens |
2 | CONCLUSION: Clotrimazole displayed a strong inhibitory effect against hCE2, which might be used as a potential combined agent co-administrated with CPT-11 to alleviate the hCE2-mediated severe side effects. | Irinotecan | carboxylesterase 2 | Homo sapiens |
3 | CONCLUSION: Clotrimazole displayed a strong inhibitory effect against hCE2, which might be used as a potential combined agent co-administrated with CPT-11 to alleviate the hCE2-mediated severe side effects. | Irinotecan | carboxylesterase 2 | Homo sapiens |