Title : miR-24 targets SARS-CoV-2 co-factor Neuropilin-1 in human brain microvascular endothelial cells: Insights for COVID-19 neurological manifestations.

Pub. Date : 2021 Feb 2

PMID : 33564755






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 miR-24 targets SARS-CoV-2 co-factor Neuropilin-1 in human brain microvascular endothelial cells: Insights for COVID-19 neurological manifestations. mir-24 neuropilin 1 Homo sapiens
2 By combining bioinformatic and functional approaches, we identified miR-24 as a regulator of Neuropilin-1 transcription. mir-24 neuropilin 1 Homo sapiens
3 Since Neuropilin-1 has been shown to play a key role in the endothelium-mediated regulation of the blood-brain barrier, we validated miR-24 as a functional modulator of Neuropilin-1 in human brain microvascular endothelial cells (hBMECs), which are the most suitable cell line for an in vitro blooda$"brain barrier model. mir-24 neuropilin 1 Homo sapiens
4 Since Neuropilin-1 has been shown to play a key role in the endothelium-mediated regulation of the blood-brain barrier, we validated miR-24 as a functional modulator of Neuropilin-1 in human brain microvascular endothelial cells (hBMECs), which are the most suitable cell line for an in vitro blooda$"brain barrier model. mir-24 neuropilin 1 Homo sapiens