Title : Structural insights into the regulation of human serine palmitoyltransferase complexes.

Pub. Date : 2021 Mar

PMID : 33558761






1 Functional Relationships(s)
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Protein Name
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1 In humans, the first and rate-limiting step of sphingolipid synthesis is catalyzed by the serine palmitoyltransferase holocomplex, which consists of catalytic components (SPTLC1 and SPTLC2) and regulatory components (ssSPTa and ORMDL3). Sphingolipids serine palmitoyltransferase long chain base subunit 2 Homo sapiens