Title : Alantolactone alleviates collagen-induced arthritis and inhibits Th17 cell differentiation through modulation of STAT3 signalling.

Pub. Date : 2021 Dec

PMID : 33556301






1 Functional Relationships(s)
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1 RESULTS: In CIA mice, alantolactone at 50 mg/kg attenuated RA symptoms, including high arthritis scores, infiltrating inflammatory cells, synovial hyperplasia, bone erosion and levels of the proinflammatory cytokines TNF-alpha, IL-6 and IL-17A, but not IL-10 in paw tissues. alantolactone interleukin 6 Mus musculus