Title : The "C3aR Antagonist" SB290157 is a Partial C5aR2 Agonist.

Pub. Date : 2020

PMID : 33551801






1 Functional Relationships(s)
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1 Given these issues, in the present study we aimed to further explore SB290157"s pharmacological selectivity by screening the drug against three human anaphylatoxin receptors, C3aR, C5aR1 and C5aR2, using cell models. SB 290157 complement C5a receptor 1 Homo sapiens