Protein Name | complement C5a receptor 1 |
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Organism | Homo sapiens |
Gene ID | 728 |
Gene Symbol | C5AR1 |
UniProt | P21730 (C5AR1_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
623
Total Number of Articles : 847 |
Description |
complement C5a receptor 1 |
Gene Summary |
Enables G protein-coupled receptor activity and complement component C5a receptor activity. Involved in several processes, including complement component C5a signaling pathway; mRNA transcription by RNA polymerase II; and positive regulation of ERK1 and ERK2 cascade. Located in apical part of cell and basolateral plasma membrane. Biomarker of Alzheimer's disease; asthma; chronic obstructive pulmonary disease; rhinitis; and severe acute respiratory syndrome. [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |