Protein Name complement C5a receptor 1
Organism Homo sapiens
Gene ID 728
Gene Symbol


UniProt P21730 (C5AR1_HUMAN)
Relationships Total Number of functionally related compound(s) : 623
Total Number of Articles : 847

complement C5a receptor 1

Gene Summary

Enables G protein-coupled receptor activity and complement component C5a receptor activity. Involved in several processes, including complement component C5a signaling pathway; mRNA transcription by RNA polymerase II; and positive regulation of ERK1 and ERK2 cascade. Located in apical part of cell and basolateral plasma membrane. Biomarker of Alzheimer's disease; asthma; chronic obstructive pulmonary disease; rhinitis; and severe acute respiratory syndrome. [provided by Alliance of Genome Resources, Apr 2022]

  • C5a anaphylatoxin chemotactic receptor 1
  • C5a anaphylatoxin receptor
  • C5a ligand
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