Title : Comparing the inhibitory abilities of epigallocatechin-3-gallate and gallocatechin gallate against tyrosinase and their combined effects with kojic acid.

Pub. Date : 2021 Jul 1

PMID : 33545599






1 Functional Relationships(s)
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1 Both EGCG and GCG inhibited tyrosinase in a mixed manner with the IC50 values of 39.4 +- 0.54 muM and 36.8 +- 0.21 muM, and showed a synergism with their combination, while EGCG and GCG combined with kojic acid (IC50 = 19.2 +- 0.26 muM) exhibited antagonism and additive effect, respectively. kojic acid tyrosinase Homo sapiens