Title : Preemptive screening of DPYD as part of clinical practice: high prevalence of a novel exon 4 deletion in the Finnish population.

Pub. Date : 2021 May

PMID : 33544210






2 Functional Relationships(s)
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1 In this article, we describe the application of upfront DPD screening in Finnish patients, as a part of daily clinical practice, which was based on a comprehensive DPYD gene analysis, measurements of enzyme activity and plasma uracil concentrations. Uracil dihydropyrimidine dehydrogenase Homo sapiens
2 The DPD deficiency in these patients was further confirmed via analysis of the DPD activity and plasma uracil levels. Uracil dihydropyrimidine dehydrogenase Homo sapiens