Pub. Date : 2021 Feb 17
PMID : 33538575
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Abeta Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors. | Calcium | amyloid beta precursor protein | Homo sapiens |
| 2 | Here, we studied the effects on calcium homeostasis caused by the formation of Abeta oligomeric assemblies. | Calcium | amyloid beta precursor protein | Homo sapiens |
| 3 | We found that Abeta oligomers cause a rapid influx of calcium ions (Ca2+) across the cell membrane by rapidly activating extrasynaptic N-methyl-d-aspartate (NMDA) receptors and, to a lower extent, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. | Calcium | amyloid beta precursor protein | Homo sapiens |