Title : Palbociclib negatively regulates fatty acid synthesis due to upregulation of AMPKα and miR-33a levels to increase apoptosis in Panc-1 and MiaPaCa-2 cells.

Pub. Date : 2022 Feb

PMID : 33538066






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Fatty acids (FA) synthesis mechanism has various regulators such as fatty acid synthase (FASN), AMP-regulated protein kinase (AMPK) or mammalian target of rapamycin (mTOR), which are aberrantly dysregulated in various pancreatic cancer cells. Fatty Acids protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 Fatty acids (FA) synthesis mechanism has various regulators such as fatty acid synthase (FASN), AMP-regulated protein kinase (AMPK) or mammalian target of rapamycin (mTOR), which are aberrantly dysregulated in various pancreatic cancer cells. Fatty Acids protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens