Title : rHDL modeling and the anchoring mechanism of LCAT activation.

Pub. Date : 2021

PMID : 33518511






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Lecithin:cholesterol-acyl transferase (LCAT) plays a major role in cholesterol metabolism as it is the only extracellular enzyme able to esterify cholesterol. Cholesterol lecithin-cholesterol acyltransferase Homo sapiens
2 Lecithin:cholesterol-acyl transferase (LCAT) plays a major role in cholesterol metabolism as it is the only extracellular enzyme able to esterify cholesterol. Cholesterol lecithin-cholesterol acyltransferase Homo sapiens
3 Lecithin:cholesterol-acyl transferase (LCAT) plays a major role in cholesterol metabolism as it is the only extracellular enzyme able to esterify cholesterol. Cholesterol lecithin-cholesterol acyltransferase Homo sapiens
4 In fact, genetic alterations affecting LCAT functionality may cause a severe reduction in plasma levels of HDL-cholesterol with important clinical consequences. Cholesterol lecithin-cholesterol acyltransferase Homo sapiens
5 We employed a combination of structural bioinformatics procedures to deepen the insights into the HDL-LCAT interplay that promotes LCAT activation and cholesterol esterification. Cholesterol lecithin-cholesterol acyltransferase Homo sapiens