Protein Name lecithin-cholesterol acyltransferase
Organism Homo sapiens
Gene ID 3931
Gene Symbol


UniProt P04180 (LCAT_HUMAN), A0A140VK24 (A0A140VK24_HUMAN)
Relationships Total Number of functionally related compound(s) : 452
Total Number of Articles : 799

lecithin-cholesterol acyltransferase

Gene Summary

This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency. [provided by RefSeq, Jul 2008]

  • phosphatidylcholine-sterol acyltransferase
  • 1-alkyl-2-acetylglycerophosphocholine esterase
  • PAF acetylhydrolase
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