Pub. Date : 2021 Mar 12
PMID : 33516880
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Sub-toxic levels of cobalt ions impair chondrocyte mechanostranduction via HDAC6-dependent primary cilia shortening. | Cobalt | histone deacetylase 6 | Homo sapiens |
2 | Moreover, cobalt ions induced HDAC6-dependent primary cilia disassembly, which was associated with either cytoplasmic or ciliary alpha-tubulin deacetylation. | Cobalt | histone deacetylase 6 | Homo sapiens |
3 | Thus, sub-toxic levels of cobalt ions impaired chondrocyte mechanotransduction via HDAC6 activation, which was associated with tubulin deacetylation and primary cilia shortening. | Cobalt | histone deacetylase 6 | Homo sapiens |