Pub. Date : 2021 May
PMID : 33516753
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This paper describes the identification of a key excipient, sodium laurate, which can solubilize LPL in an isotonic environment without heparin or concentrated glycerol. | lauric acid | lipoprotein lipase | Homo sapiens |
| 2 | A follow-up multi-variant study was performed to identify the effect of sodium laurate and its interaction with sodium chloride on the solubility and processing conditions of LPL. | lauric acid | lipoprotein lipase | Homo sapiens |
| 3 | The LPL concentration (up to 14 mg/mL) achievable in pharmaceutically relevant and salt-free conditions was identified to be closely correlated to the concentration of sodium laurate, which was co-concentrated with LPL. | lauric acid | lipoprotein lipase | Homo sapiens |
| 4 | The LPL concentration (up to 14 mg/mL) achievable in pharmaceutically relevant and salt-free conditions was identified to be closely correlated to the concentration of sodium laurate, which was co-concentrated with LPL. | lauric acid | lipoprotein lipase | Homo sapiens |
| 5 | The results that sodium laurate increases stability of LPL characterized by differential scanning calorimetry and UV absorbance spectra suggests that the mechanism of solubilization of LPL by sodium laurate is related to LPL structural stabilization. | lauric acid | lipoprotein lipase | Homo sapiens |
| 6 | The results that sodium laurate increases stability of LPL characterized by differential scanning calorimetry and UV absorbance spectra suggests that the mechanism of solubilization of LPL by sodium laurate is related to LPL structural stabilization. | lauric acid | lipoprotein lipase | Homo sapiens |
| 7 | The results that sodium laurate increases stability of LPL characterized by differential scanning calorimetry and UV absorbance spectra suggests that the mechanism of solubilization of LPL by sodium laurate is related to LPL structural stabilization. | lauric acid | lipoprotein lipase | Homo sapiens |
| 8 | The results that sodium laurate increases stability of LPL characterized by differential scanning calorimetry and UV absorbance spectra suggests that the mechanism of solubilization of LPL by sodium laurate is related to LPL structural stabilization. | lauric acid | lipoprotein lipase | Homo sapiens |
| 9 | The results that sodium laurate increases stability of LPL characterized by differential scanning calorimetry and UV absorbance spectra suggests that the mechanism of solubilization of LPL by sodium laurate is related to LPL structural stabilization. | lauric acid | lipoprotein lipase | Homo sapiens |
| 10 | The results that sodium laurate increases stability of LPL characterized by differential scanning calorimetry and UV absorbance spectra suggests that the mechanism of solubilization of LPL by sodium laurate is related to LPL structural stabilization. | lauric acid | lipoprotein lipase | Homo sapiens |