Protein Name lipoprotein lipase
Organism Homo sapiens
Gene ID 4023
Gene Symbol


UniProt P06858 (LIPL_HUMAN), A0A1B1RVA9 (A0A1B1RVA9_HUMAN)
Relationships Total Number of functionally related compound(s) : 754
Total Number of Articles : 1990

lipoprotein lipase

Gene Summary

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]

  • lipoprotein lipase
  • phospholipase A1
  • HDLCQ11
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