Title : A Novel Long-Term Graves' Disease Animal Model Confirmed by Functional Thyrotropin Receptor Antibodies.

Pub. Date : 2020 Dec

PMID : 33511085






3 Functional Relationships(s)
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1 In contrast, at week 17, in Ad-TSHR mice, the mean TBII, TBAb, and TSAb levels were 40 IU/L (40; 40); 62% inhibition (38; 69), and 116% SRR (97; 185), respectively; at week 27, they were 40 IU/L (39; 40); 65% inhibition (34; 80) and 95% SRR (63; 187), respectively. Tetrabutylammonium bromide thyroid stimulating hormone receptor Mus musculus
2 Three serum samples from Ad-TSHR mice (38%) demonstrated dual TBAb/TSAb positivity. Tetrabutylammonium bromide thyroid stimulating hormone receptor Mus musculus
3 All TBAb- and TSAb-positive Ad-TSHR-immunized mice were TBII-positive. Tetrabutylammonium bromide thyroid stimulating hormone receptor Mus musculus