Protein Name thyroid stimulating hormone receptor
Organism Mus musculus
Gene ID 22095
Gene Symbol

Tshr

UniProt P47750 (TSHR_MOUSE), Q78U67 (Q78U67_MOUSE)
Relationships Total Number of functionally related compound(s) : 353
Total Number of Articles : 295
Description

thyroid stimulating hormone receptor

Gene Summary

Enables thyroid-stimulating hormone receptor activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including adult locomotory behavior; dopaminergic neuron differentiation; and inner ear development. Located in plasma membrane. Is expressed in bladder; renal vasculature; thyroid gland; and thyroid gland lobe. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in Graves' disease; cardiomyopathy; congenital nongoitrous hypothyroidism 1; and mitral valve prolapse. Orthologous to human TSHR (thyroid stimulating hormone receptor). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • thyrotropin receptor
  • TSH-R
  • hypothroid
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Properties