Title : Cucurbitacin B Diminishes Metastatic Behavior of Cholangiocarcinoma Cells by Suppressing Focal Adhesion Kinase.

Pub. Date : 2021 Jan 1

PMID : 33507702






2 Functional Relationships(s)
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1 Further molecular studies demonstrated that FAK inhibitor-14 and cucurbitacin B downregulated the expression of metastasis-associated proteins including MMP-9, ICAM-1 and VEGF. cucurbitacin B matrix metallopeptidase 9 Homo sapiens
2 Consequently, exposure to cucurbitacin B inhibited the production of MMP-9 enzyme in CCA cells similar to FAK inhibitor-14 treatment. cucurbitacin B matrix metallopeptidase 9 Homo sapiens