Title : Sorafenib not only impairs endothelium-dependent relaxation but also promotes vasoconstriction through the upregulation of vasoconstrictive endothelin type B receptors.

Pub. Date : 2021 Mar 1

PMID : 33503445






1 Functional Relationships(s)
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1 The results showed that sorafenib impairs endothelium-dependent vasodilation due to decreased NO levels and the low expression of eNOS and iNOS. Sorafenib nitric oxide synthase 3 Rattus norvegicus