Pub. Date : 2021 Feb
PMID : 33502024
3 Functional Relationships(s)Download |
||||||
Sentence | Compound Name | Protein Name | Organism |
|||
1 | Renal I/R increased in tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) levels, and histopathological changes but these effects were inhibited with umbelliferone pretreatment. | 7-hydroxycoumarin | interleukin 6 | Rattus norvegicus | ||
2 | Renal I/R increased in tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) levels, and histopathological changes but these effects were inhibited with umbelliferone pretreatment. | 7-hydroxycoumarin | interleukin 6 | Rattus norvegicus | ||
3 | The oral treatment of umbelliferone markedly reversed the oxidative stress, inflammation, and histopathological changes by increasing in the levels of SOD, GSH, and eNOS, decreasing in the levels of MDA, MPO, TNF-alpha, and IL-6 in distant organ injury induced by renal I/R. | 7-hydroxycoumarin | interleukin 6 | Rattus norvegicus |