Title : Ameliorative effect of umbelliferone in remote organ injury induced by renal ischemia-reperfusion in rats.

Pub. Date : 2021 Feb

PMID : 33502024






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Renal I/R increased in tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) levels, and histopathological changes but these effects were inhibited with umbelliferone pretreatment. 7-hydroxycoumarin interleukin 6 Rattus norvegicus
2 Renal I/R increased in tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) levels, and histopathological changes but these effects were inhibited with umbelliferone pretreatment. 7-hydroxycoumarin interleukin 6 Rattus norvegicus
3 The oral treatment of umbelliferone markedly reversed the oxidative stress, inflammation, and histopathological changes by increasing in the levels of SOD, GSH, and eNOS, decreasing in the levels of MDA, MPO, TNF-alpha, and IL-6 in distant organ injury induced by renal I/R. 7-hydroxycoumarin interleukin 6 Rattus norvegicus