Pub. Date : 2021
PMID : 33500617
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The mechanism was probably attributed to the accumulation of PLD in the skin tissues during the long-term circulation and further the induction of ROS to cause the oxidative damage of keratinocytes owing to the sustained release of doxorubicin from PLD. | Reactive Oxygen Species | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
2 | Conclusion: The ROS generation induced by the administration of PLD has been identified to be a crucial factor in the development of HFS, which could be used as a potential therapeutic target to alleviate the HFS symptom of PLD administration. | Reactive Oxygen Species | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
3 | Conclusion: The ROS generation induced by the administration of PLD has been identified to be a crucial factor in the development of HFS, which could be used as a potential therapeutic target to alleviate the HFS symptom of PLD administration. | Reactive Oxygen Species | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |