Title : Effect of DNA Glycosylases OGG1 and Neil1 on Oxidized G-Rich Motif in the KRAS Promoter.

Pub. Date : 2021 Jan 24

PMID : 33498912






1 Functional Relationships(s)
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1 As guanine under oxidative stress can be oxidized to 8-oxoguanine (8OG), we investigated the capacity of glycosylases 8-oxoguanine glycosylase (OGG1) and endonuclease VIII-like 1 (Neil1) to excise 8OG from 32R, either in duplex or G-quadruplex (G4) conformation. Guanine 8-oxoguanine DNA glycosylase Homo sapiens