Title : Inhibition of ROS/NLRP3/Caspase-1 mediated pyroptosis attenuates cadmium-induced apoptosis in duck renal tubular epithelial cells.

Pub. Date : 2020 Oct 23

PMID : 33497945






3 Functional Relationships(s)
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1 The results evidenced that Cd significantly increased the releases of interleukin-18 (IL-18) and interleukin-1beta (IL-1beta), lactate dehydrogenase (LDH) and nitric oxide (NO), relative conductivity and cellular reactive oxygen species (ROS) level. Cadmium interleukin 18 Homo sapiens
2 The results evidenced that Cd significantly increased the releases of interleukin-18 (IL-18) and interleukin-1beta (IL-1beta), lactate dehydrogenase (LDH) and nitric oxide (NO), relative conductivity and cellular reactive oxygen species (ROS) level. Cadmium interleukin 18 Homo sapiens
3 Simultaneously, Cd also markedly upregulated NLRP3, Caspase-1, ASC, NEK7, IL-1beta and IL-18 mRNA levels and NLRP3, Caspase-1 p20, GSDMD and ASC protein levels. Cadmium interleukin 18 Homo sapiens