Title : G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.

Pub. Date : 2021 Feb 4

PMID : 33497611






1 Functional Relationships(s)
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1 They act in a non-redundant manner to anchor the tuberous sclerosis complex (TSC) protein complex to lysosomes and suppress activation of the metabolic master regulator mechanistic target of rapamycin complex 1 (mTORC1) by amino acids and insulin. Sirolimus insulin Homo sapiens