Pub. Date : 2021 Jan 21
PMID : 33479328
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Hyperglycemia-induced VEGF and ROS production in retinal cells is inhibited by the mTOR inhibitor, rapamycin. | Sirolimus | vascular endothelial growth factor A | Rattus norvegicus |
2 | Determine the impact of the mTOR inhibitor, rapamycin, on the hyperglycemia-induced expression of vascular endothelial growth factor (VEGF) and the production of reactive oxygen species (ROS) in retinal cells. | Sirolimus | vascular endothelial growth factor A | Rattus norvegicus |
3 | Determine the impact of the mTOR inhibitor, rapamycin, on the hyperglycemia-induced expression of vascular endothelial growth factor (VEGF) and the production of reactive oxygen species (ROS) in retinal cells. | Sirolimus | vascular endothelial growth factor A | Rattus norvegicus |
4 | In rat retina, rapamycin attenuates the diabetes-induced VEGF overexpression, and in cultured Muller cells and HRMECs, inhibits the hyperglycemia-induced boost ROS. | Sirolimus | vascular endothelial growth factor A | Rattus norvegicus |