Title : The tyrosine kinase v-Src modifies cytotoxicities of anticancer drugs targeting cell division.

Pub. Date : 2021 Feb

PMID : 33465289






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 v-Src directly phosphorylates Tyr-15 of cyclin-dependent kinase 1 (CDK1), thereby causing mitotic slippage and reduction in Eg5 inhibitor cytotoxicity. Tyrosine SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens