Title : Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.

Pub. Date : 2021 Nov 17

PMID : 33461297






5 Functional Relationships(s)
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1 Recent data have shown anti-inflammatory effects for trans-resveratrol (RSV) and rosmarinic acid (RA) in various immune-competent cell models through reduction of lipopolysaccharide (LPS)-induced interleukin 6 (IL-6) release. Resveratrol interleukin 6 Homo sapiens
2 Recent data have shown anti-inflammatory effects for trans-resveratrol (RSV) and rosmarinic acid (RA) in various immune-competent cell models through reduction of lipopolysaccharide (LPS)-induced interleukin 6 (IL-6) release. Resveratrol interleukin 6 Homo sapiens
3 Recent data have shown anti-inflammatory effects for trans-resveratrol (RSV) and rosmarinic acid (RA) in various immune-competent cell models through reduction of lipopolysaccharide (LPS)-induced interleukin 6 (IL-6) release. Resveratrol interleukin 6 Homo sapiens
4 Next, the IL-6 modulatory effect of 100 muM RSV was studied in LPS-treated immune-competent HGF-1 cells. Resveratrol interleukin 6 Homo sapiens
5 After 6 h of treatment, RSV reduced the LPS-induced IL-6 gene expression and protein release by -46.2 +- 12.7 and -73.9 +- 2.99%, respectively. Resveratrol interleukin 6 Homo sapiens