Pub. Date : 2021 Jan
PMID : 33424398
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In silico evaluation of flavonoids as effective antiviral agents on the spike glycoprotein of SARS-CoV-2. | Flavonoids | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 2 | In the current study, an in silico approach is carried out as a means of inhibiting the spike protein of the novel coronavirus by flavonoids from natural sources that possess both antiviral and anti-inflammatory properties. | Flavonoids | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 3 | The methodology is focused on molecular docking of 10 flavonoid compounds that are docked with the spike protein of SARS-CoV-2, to determine the highest binding affinity at the binding site. | Flavonoids | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 4 | The flavonoid naringin showed the least binding energy of -9.8 Kcal/mol with the spike protein which was compared with the standard drug, dexamethasone which is being repurposed to treat critically ill patients. | Flavonoids | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |