PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33424398-0 2021 In silico evaluation of flavonoids as effective antiviral agents on the spike glycoprotein of SARS-CoV-2. Flavonoids 24-34 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 72-77 33424398-4 2021 In the current study, an in silico approach is carried out as a means of inhibiting the spike protein of the novel coronavirus by flavonoids from natural sources that possess both antiviral and anti-inflammatory properties. Flavonoids 130-140 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 88-93 33424398-5 2021 The methodology is focused on molecular docking of 10 flavonoid compounds that are docked with the spike protein of SARS-CoV-2, to determine the highest binding affinity at the binding site. Flavonoids 54-63 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 99-104 33424398-7 2021 The flavonoid naringin showed the least binding energy of -9.8 Kcal/mol with the spike protein which was compared with the standard drug, dexamethasone which is being repurposed to treat critically ill patients. Flavonoids 4-13 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 81-86