Title : Role of autophagy in regulating interleukin-10 and the responses to corticosteroids and statins in asthma.

Pub. Date : 2021 Dec

PMID : 33423318






1 Functional Relationships(s)
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1 In macrophages in-vitro, budesonide and simvastatin inhibited rapamycin-induced autophagy as well as autophagic flux, with reduced expression of beclin-1 and LC3, but enhanced the accumulation of p62 and increased expression of IL-10, which itself further inhibited autophagy in macrophages. Sirolimus beclin 1 Homo sapiens