Pub. Date : 2021 May
PMID : 33420900
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ginsenoside Rb1 Protects Human Umbilical Vein Endothelial Cells against High Glucose-Induced Mitochondria-Related Apoptosis through Activating SIRT3 Signalling Pathway. | Glucose | RB transcriptional corepressor 1 | Homo sapiens |
| 2 | OBJECTIVE: To investigate whether ginsenoside Rb1 (Rb1) can protect human umbilical vein endothelial cells (HUVECs) against high glucose-induced apoptosis and examine the underlying mechanism. | Glucose | RB transcriptional corepressor 1 | Homo sapiens |
| 3 | OBJECTIVE: To investigate whether ginsenoside Rb1 (Rb1) can protect human umbilical vein endothelial cells (HUVECs) against high glucose-induced apoptosis and examine the underlying mechanism. | Glucose | RB transcriptional corepressor 1 | Homo sapiens |
| 4 | RESULTS: Rb1 ameliorated survival in cells in which apoptosis was induced by high glucose (P<0.05 or P<0.01). | Glucose | RB transcriptional corepressor 1 | Homo sapiens |
| 5 | The effect of Rb1 against high glucose-induced mitochondria-related apoptosis was restrained by 3-TYP (P<0.05 or P<0.01). | Glucose | RB transcriptional corepressor 1 | Homo sapiens |
| 6 | CONCLUSION: Rb1 could protect HUVECs from high glucose-induced apoptosis by promoting mitochondrial function and suppressing oxidative stress through the SIRT3 signalling pathway. | Glucose | RB transcriptional corepressor 1 | Homo sapiens |