Title : Combination of Hydroxychloroquine and Indapamide Attenuates Neurodegeneration in Models Relevant to Multiple Sclerosis.

Pub. Date : 2021 Jan

PMID : 33410109






1 Functional Relationships(s)
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1 In vitro, indapamide had robust hydroxyl scavenging activity, while HCQ and indapamide alone and in combination protected against iron-induced neuronal killing; TNF-alpha levels in activated microglia were reduced by either drug alone, without additional combination effects. Hydroxychloroquine tumor necrosis factor Mus musculus