Title : Development of a Novel SNAP-Epitope Tag/Near-Infrared Imaging Assay to Quantify G Protein-Coupled Receptor Degradation in Human Cells.

Pub. Date : 2021 Apr

PMID : 33402011






3 Functional Relationships(s)
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1 Remarkably, endogenous beta2-adrenergic receptor/ADRB2 dynamic mass redistribution functional responses to norepinephrine were significantly decreased following CHX treatment, with a time course equivalent to that observed with the SNAP-ADRB2 degradation assay. Norepinephrine adrenoceptor beta 2 Homo sapiens
2 Remarkably, endogenous beta2-adrenergic receptor/ADRB2 dynamic mass redistribution functional responses to norepinephrine were significantly decreased following CHX treatment, with a time course equivalent to that observed with the SNAP-ADRB2 degradation assay. Norepinephrine adrenoceptor beta 2 Homo sapiens
3 Remarkably, endogenous beta2-adrenergic receptor/ADRB2 dynamic mass redistribution functional responses to norepinephrine were significantly decreased following CHX treatment, with a time course equivalent to that observed with the SNAP-ADRB2 degradation assay. Norepinephrine adrenoceptor beta 2 Homo sapiens