Title : MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit.

Pub. Date : 2021 Jan 4

PMID : 33398005






1 Functional Relationships(s)
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1 We discovered that ER+ breast cancer cells survive tamoxifen and letrozole treatments through upregulation of minichromosome maintenance proteins (MCMs), including MCM3, which are key molecules in the cell cycle and DNA replication. Tamoxifen epiregulin Homo sapiens