Title : Cardiovascular and renal safety of metformin in patients with diabetes and moderate or severe chronic kidney disease: Observations from the EXSCEL and SAVOR-TIMI 53 cardiovascular outcomes trials.

Pub. Date : 2021 May

PMID : 33394543






2 Functional Relationships(s)
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1 Metformin effect on eGFR slope was calculated using a mixed model-repeated measures (MMRM) analysis, and the number of lactic acidosis events was tabulated. Metformin epidermal growth factor receptor Homo sapiens
2 An improvement in eGFR slope was observed with metformin in the CKD stage 3B cohort in SAVOR, but not in other groups. Metformin epidermal growth factor receptor Homo sapiens