Title : Environmental exposures and the etiopathogenesis of Alzheimer's disease: The potential role of BACE1 as a critical neurotoxic target.

Pub. Date : 2021 Apr

PMID : 33393683






1 Functional Relationships(s)
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1 Here, we critically review research on environmental neurotoxicants such as metals, pesticides, herbicides, fungicides, polyfluoroalkyl substances, heterocyclic aromatic amines, advanced glycation end products, and acrolein that modulate BACE1 and potential mechanisms of action. heterocyclic aromatic amines beta-secretase 1 Homo sapiens