Title : A novel STAT3 inhibitor W2014-S regresses human non-small cell lung cancer xenografts and sensitizes EGFR-TKI acquired resistance.

Pub. Date : 2021

PMID : 33391507






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 W2014-S with pharmacophore structure of imidazopyridine, which was firstly reported to be utilized in STAT3 inhibitor discovery, was screened out as a potent STAT3 inhibitor from a library of small molecules. imidazopyridine signal transducer and activator of transcription 3 Homo sapiens
2 W2014-S with pharmacophore structure of imidazopyridine, which was firstly reported to be utilized in STAT3 inhibitor discovery, was screened out as a potent STAT3 inhibitor from a library of small molecules. imidazopyridine signal transducer and activator of transcription 3 Homo sapiens