Title : Stiffness of Nanoparticulate Mineralized Collagen Scaffolds Triggers Osteogenesis via Mechanotransduction and Canonical Wnt Signaling.

Pub. Date : 2021 Mar

PMID : 33382197






1 Functional Relationships(s)
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1 The results indicate that increasing MC-GAG stiffness induces osteogenic differentiation via the mechanotransduction mediators YAP/TAZ and the canonical Wnt signaling pathway, whereas the canonical BMPR signaling pathway is activated independent of stiffness. Glycosaminoglycans Yes1 associated transcriptional regulator Homo sapiens